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Total Immunoglobulin E (IgE) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE), a type of antibody your body produces in response to allergens or infections.

Quick summary

["IgE levels help identify allergies or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39606-9
Short code
Rabbit Epith IgE/IgE total %
Synonyms
Rabbit Epith IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system that reacts to substances like pollen, dust mites, or certain foods. High levels may signal allergies, asthma, or other immune conditions.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, skin rashes, or breathing difficulties that suggest allergies or immune-related issues.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab, where it is analyzed to measure IgE levels using a specialized immunoassay method.

What Do Results Mean?

Results are compared to standard reference ranges. Elevated IgE levels may indicate allergies, asthma, or other immune disorders, while normal or low levels may suggest no significant immune response to allergens.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

What causes elevated IgE levels?
Elevated IgE levels are commonly linked to allergies (e.g., to pollen, pet dander, or foods), asthma, or conditions like atopic dermatitis. They can also occur with certain infections or autoimmune responses.
What if my IgE levels are normal?
If your IgE levels are within the normal range, it generally means your immune system isn’t overreacting to common allergens. However, symptoms like allergies or asthma may still require further evaluation.
Can IgE levels change over time?
Yes, IgE levels can fluctuate depending on exposure to allergens, immune responses, or underlying health conditions. Regular monitoring may be needed if you have ongoing symptoms or conditions like allergies or asthma.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy