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Vitamin D Binding Protein (DBP) Concentration (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of vitamin D binding protein in your blood serum. It helps assess how vitamin D is transported in your body and may be used alongside other vitamin D tests to evaluate vitamin D status.

Quick summary

["Your doctor may order this test to help diagnose or monitor conditions related to vitamin D metabolism or transport."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70865-1
Short code
RABV IgM Titr CSF IF
Synonyms
RABV IgM Titr CSF IF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may request this test if you have symptoms or risk factors for vitamin D deficiency, such as chronic kidney disease, malabsorption disorders, or certain genetic conditions. It can also be part of a broader evaluation when vitamin D levels are abnormal or when monitoring treatment for conditions affecting vitamin D metabolism.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for 8–12 hours before the test if your doctor has specific instructions. Bring any medications you’re currently taking, as some may affect results.

How the Test Is Performed

A blood sample is drawn from a vein in your arm by a healthcare professional. The sample is sent to a lab for analysis using an immunoassay method to measure the concentration of vitamin D binding protein.

What the Results Mean

Results are reported as a concentration value (e.g., grams per liter). While reference ranges vary by lab, abnormal levels may indicate conditions affecting vitamin D transport or related metabolic processes. Your doctor will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Vitamin D Binding Protein (Serum)

Frequently asked questions

What does a high level of vitamin D binding protein mean?
High levels may be associated with certain genetic disorders (e.g., familial chylomicronemia syndrome) or conditions affecting protein synthesis, though they are less commonly linked to vitamin D deficiency alone. Further evaluation by your doctor may include additional tests or clinical correlation.
What does a low level of vitamin D binding protein mean?
Low levels are less frequently isolated in isolation but could be part of a broader assessment if you have symptoms of protein-related disorders or if your vitamin D metabolism is being evaluated alongside other tests.
Can vitamin D binding protein levels change with diet?
Vitamin D binding protein itself is not directly influenced by diet, but its function is tied to overall protein metabolism. Dietary changes that affect protein intake or liver/kidney function may indirectly impact its levels, so discuss any significant dietary changes with your doctor before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy