Complete Blood Count (CBC): What You Need to Know
A blood test that detects antibodies against Rickettsia akari, the bacteria that causes rickettsialpox, using immunofluorescence technology.
{"This test checks if your immune system has produced antibodies against Rickettsia akari bacteria","It helps diagnose rickettsialpox, a mite-borne infection causing fever and skin lesions","The test uses immunofluorescence to detect antibodies in your blood sample","A positive result indicates current or past infection with this specific rickettsial organism"}
Key facts at a glance
- LOINC
- 29708-5
- Short code
- RICKAK
- Synonyms
- R akari Ab Ser Ql IF
- Category
- cardiac
- Sample
- serum
- Container
- Serum separator tube (SST) or red top tube
- Units
- N/A
- Ref low
- 0
- Ref high
- 1
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- Indirect Immunofluorescence Assay (IFA)
- CPT
- 86757
- SNOMED
- 371949004
- Specimen volume
- 1-2 mL of serum minimum
- Stability
- Serum: 2-8°C for up to 7 days; -20°C or below for longer storage. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 50
- Lipemia max
- 40
- Icterus max
- 20
- TAT
- 48–168 hours
- Order
- routine
A complete blood count (CBC) is a common blood test that measures and evaluates the cells in your blood. It provides important information about the numbers and types of red blood cells, white blood cells, and platelets, helping doctors assess your overall health and detect a variety of disorders such as anemia, infection, and bleeding conditions.
The Rickettsia akari Antibody test is a specialized blood test that looks for specific antibodies (immune system proteins) in your blood that your body produces to fight Rickettsia akari bacteria. This bacteria causes a disease called rickettsialpox, which is transmitted to humans through mite bites. The test uses a technique called immunofluorescence, which uses special fluorescent dyes to detect the presence of these antibodies in your serum (the liquid part of your blood).
The test is performed by drawing a small sample of blood from a vein in your arm using a needle. The blood is collected in a tube and sent to a laboratory for analysis. There is no special preparation required, and the procedure usually takes only a few minutes. You may feel a brief sting when the needle is inserted, but the discomfort is typically minimal.
A healthcare professional will draw a small blood sample from a vein in your arm. This sample is then sent to a laboratory where technicians will use immunofluorescence methods to detect whether antibodies against Rickettsia akari are present. The test can determine if you have been infected with this specific type of rickettsial bacteria.
Your doctor may recommend a CBC for various reasons, such as to check for anemia, detect infections, monitor the effects of medications, or evaluate the status of chronic conditions like leukemia or polycythemia. It is often part of a routine physical exam to provide a snapshot of your overall health and identify any potential issues that may need further investigation.
Your doctor may order this test if you have symptoms of rickettsialpox, which typically include fever, headache, muscle aches, and a distinctive skin rash that begins as a small bump (eschar) at the bite site followed by a widespread rash. This test is particularly useful when other conditions have been ruled out and your symptoms suggest a rickettsial infection.
The results of a CBC are interpreted by looking at the levels of each cell type. Low red blood cell counts may indicate anemia, while high counts can suggest dehydration or other conditions. Abnormal white blood cell counts can point to infection or immune system disorders, and platelet levels affect blood clotting. Your doctor will explain what your specific results mean in the context of your symptoms and medical history, and may order additional tests if needed.
A positive result means that antibodies to Rickettsia akari were detected in your blood, indicating that you have or recently had a rickettsialpox infection. A negative result means no antibodies were detected, which could mean you do not have the infection, or it may be too early in the infection for antibodies to be detectable. Your healthcare provider will interpret these results in conjunction with your symptoms and other test findings.
Reference range
Negative: <1:64 titer; Equivocal: 1:64 titer; Positive: >=1:128 titerN/A
No special preparation required. This is a serological test for detection of Rickettsia akari antibodies (causative agent of rickettsialpox). Recent antibiotic therapy may affect results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The Rickettsia akari antibody test is clinically significant for diagnosing rickettsialpox, a relatively rare but treatable infectious disease. Early detection and treatment with appropriate antibiotics (typically doxycycline) is important to prevent complications. While categorized as cardiac in some laboratory systems, this likely reflects that rickettsial infections can occasionally affect the cardiovascular system in severe cases, or may be part of a broader rickettsial disease panel that includes cardiac manifestations.
Frequently asked questions
Is fasting required before this test?
How long does it take to get results?
Can this test distinguish between current and past infection?
Is rickettsialpox contagious?
What happens if my test is positive?
Sources
- 1CDC - RickettsialpoxSource
- 2LOINC Code 29708-5Source
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 14, 2026. · Read our editorial policy