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Angiotensin-Converting Enzyme (ACE) Level in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of angiotensin-converting enzyme (ACE) in your blood, which plays a role in regulating blood pressure and fluid balance. It may be used to diagnose or monitor conditions like tuberculosis or certain genetic disorders.

Quick summary

["ACE levels help doctors assess conditions affecting your blood vessels and immune system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73171-1
Short code
Ramipril ind plt IgG SerPl Ql FC
Synonyms
Ramipril ind plt IgG SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order an ACE test to investigate symptoms such as chronic cough, lung issues, or kidney problems. It’s also used in diagnosing conditions like sarcoidosis, certain cancers, and genetic disorders like lymphangioleiomyomatosis (LAM).

A blood sample is drawn from a vein in your arm. The blood is then processed to separate serum or plasma for testing. The sample is analyzed using an immunoassay method to measure ACE levels.

ACE is typically measured in units per liter (U/L) or nanograms per milliliter (ng/mL), but reference ranges vary by lab and may not be provided in this summary.

Results may be above, below, or within normal ranges depending on your health status. Elevated ACE levels can suggest conditions like tuberculosis, lymphangioleiomyomatosis, or certain cancers. Lower levels might indicate liver disease or other metabolic issues. Always discuss results with your doctor.

ACE levels can fluctuate due to factors like medications, pregnancy, or recent infections. Your doctor will consider these factors when interpreting your results.

High ACE levels are often associated with tuberculosis, sarcoidosis, or certain cancers. Low ACE levels may be linked to liver disease, kidney problems, or other metabolic conditions. Your doctor will use these results alongside other tests and symptoms to guide diagnosis.

ACE testing is not typically used for routine screening but may be part of a broader evaluation for specific symptoms or suspected conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

ACE levels can be affected by medications like ACE inhibitors (used for high blood pressure) or certain chemotherapy drugs. If you’re on these medications, let your doctor know before testing.

Short name

ACE Level

Frequently asked questions

How often should I get this test?
The frequency depends on your health condition and why the test was ordered. Your doctor will determine how often to repeat it based on your treatment plan and symptoms.
Can I eat or drink before this test?
Typically, you may fast for 8–12 hours before the test, but follow your doctor’s instructions. Avoid smoking or strenuous activity for the same period.
Does this test hurt?
The blood draw may cause a brief pinch or discomfort, but it usually doesn’t last long. Most people tolerate it well. If you have a fear of needles, let your healthcare provider know.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy