Autoantibody Profile to Screen for Autoimmune Fluid Antibodies (Autoimmune Fluid Autoantibody Profile)
This test checks for antibodies that may indicate an autoimmune condition affecting body fluids, such as blood, joint fluid, or other bodily secretions.
["This screening helps identify potential autoimmune activity in fluids that could affect your health over time."]
Key facts at a glance
- LOINC
- 99927-6
- Short code
- RBC #/area Fld Auto
- Synonyms
- RBC #/area Fld Auto
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- automated-count
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects specific antibodies (autoantibodies) that target proteins in body fluids. These antibodies may signal an immune response against normal body tissues, which can occur in autoimmune diseases. The method involves analyzing fluid samples for the presence of these markers, often using immunoassay techniques to identify abnormal antibody levels.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like chronic pain, unexplained fatigue, or signs of inflammation, or if you have a family history of autoimmune diseases. It can also be part of a broader evaluation for conditions like rheumatoid arthritis, lupus, or other connective tissue disorders.
Sample Collection and Preparation
A blood sample is typically drawn from a vein in your arm. Fluid samples from joints or other sites may also be collected if indicated. The fluid is processed and tested for specific autoantibodies in a laboratory setting.
Common Conditions Monitored
This screening helps monitor autoimmune conditions where fluid-based inflammation or antibody activity is suspected, such as synovial fluid in joint diseases or serum in systemic autoimmune disorders.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results may indicate an autoimmune process affecting body fluids, prompting further testing or treatment to manage symptoms and prevent complications. Negative results suggest no significant autoimmune activity in the tested fluids, but further evaluation may still be needed if symptoms persist.
Short name
Autoimmune Fluid Antibody Screen
Frequently asked questions
What does a positive result mean?
Can this test be done at home?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy