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Serum Creatinine Concentration (Qualitative or Quantitative Screening/Confirmation)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function screening or confirmation is critical for detecting early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
58767-5
Short code
RBC #/area Smn HPF
Synonyms
RBC #/area Smn HPF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light-hpf
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for kidney disease, monitor kidney function over time, or evaluate symptoms like swelling, fatigue, or changes in urine output. It’s also used before certain procedures or medications that affect kidney function.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader panel. Bring any medications you’re taking to your appointment.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm. The process is quick and typically painless. The sample is sent to a lab for analysis.

What Are the Results?

Results are compared to standard reference ranges to determine if your kidney function is within normal limits or if further evaluation is needed. High or low levels may signal potential issues.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

None

Frequently asked questions

What causes creatinine levels to be abnormal?
Abnormally high levels may indicate kidney damage, dehydration, or conditions like heart failure or muscle disorders. Low levels could suggest overhydration or severe muscle wasting.
How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and risk factors. Follow-up may be needed if initial results are outside normal ranges.
Can diet or medications affect creatinine levels?
Yes, certain foods (like red meat), medications (e.g., NSAIDs), or supplements can temporarily influence creatinine levels. Always discuss your diet and medications with your doctor before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy