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###1: Red Blood Cell Count in Whole Blood by Manual Method

Published: August 9, 2026Updated: August 17, 2026

###3: This test measures the concentration of red blood cells in a whole-blood sample using a manual counting method. It is often used with hemoglobin and hematocrit to help evaluate anemia, polycythemia, and other blood abnormalities.

Quick summary

["###4: A manual red blood cell count helps assess the number of red cells in the blood, but results must be interpreted with other tests and your clinical history."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
790-6
Short code
RBC # Bld Manual
Synonyms
RBC # Bld Manual
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
85041
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

###5: What the Test Measures

###6: Red blood cells carry oxygen from the lungs to tissues throughout the body. The test estimates how many red blood cells are present in a measured volume of blood; it does not directly measure oxygen saturation or red-cell function.

###7: How the Test Is Performed

###8: A blood sample is collected, usually by venipuncture, and red blood cells are counted using a manual laboratory method. The technique requires trained laboratory personnel and careful sample handling and quality control.

###9: A manual red blood cell count may be ordered as part of a complete blood count or when a clinician needs to confirm an automated result. It may be considered for symptoms such as fatigue, weakness, shortness of breath, dizziness, or unusual bleeding.

###10: Understanding the Result

###11: A lower red blood cell count may be associated with anemia, blood loss, nutritional deficiencies, or other conditions, while a higher count may occur with dehydration, lung disease, or certain other disorders. Results vary with hydration, altitude, pregnancy, medications, and laboratory technique.

###12: Limitations and Follow-Up

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

###2: Manual red blood cell count

Frequently asked questions

###14: Is this the same as a complete blood count?
###15: Not necessarily. A complete blood count is a panel that includes the red blood cell count, hemoglobin, hematocrit, white blood cell count, platelet count, and other measurements. A manual red blood cell count may be performed separately or as a confirmatory test within that panel.
###16: Does the test tell me how much oxygen my blood is carrying?
###17: No. The red blood cell count estimates the number of red cells, not the amount of oxygen they are carrying or how effectively they function. Oxygen saturation is measured with a separate pulse oximeter or blood-gas test.
###18: Is a manual red blood cell count more accurate than an automated count?
###19: There is no single method that is best in every situation. Automated counts are generally faster and often more precise, but manual counting can help verify an unexpected automated result. The laboratory's method, quality controls, and your clinical circumstances determine which result is most reliable.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy