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Hemoglobin A1c (HbA1c) with 24-hour urine collection for total urinary hemoglobin

Published: August 9, 2026Updated: August 17, 2026

This test measures your long-term blood sugar control and checks for hidden hemoglobin in your urine over 24 hours, which may indicate conditions like hematuria or blood disorders.

Quick summary

["Helps track diabetes management and detect blood in urine without visible signs."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
99869-0
Short code
RBCGhost UrnS Ql Comp Assist
Synonyms
RBCGhost UrnS Ql Comp Assist
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
computer-assisted
CPT
85041
SNOMED
900000000000003001
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why HbA1c Matters in Diabetes Care

HbA1c reflects average blood sugar levels over the past 2–3 months by measuring the percentage of hemoglobin bound to glucose. It’s a key tool for diabetes management, helping doctors assess whether your treatment is effective and adjust it as needed.

Understanding Urinary Hemoglobin in Your 24-Hour Sample

The urine test checks for hemoglobin (the protein in red blood cells) that may have leaked into your urine, often due to kidney issues, bleeding disorders, or other conditions. This test helps identify hidden blood loss that isn’t visible in a routine urine dipstick.

How the Test Works: Combining Blood and Urine Data

Your blood sample is analyzed for HbA1c using standard methods (like high-performance liquid chromatography). Your 24-hour urine sample is tested for hemoglobin content, typically via immunoassay or nephelometry, to detect small amounts that might not be obvious otherwise.

Common Reasons for This Test

Doctors may order this test if you have diabetes and need to monitor both blood sugar control *and* check for conditions causing blood in urine, such as kidney disease, urinary tract infections, or bleeding disorders. It’s also used in research or specialized evaluations.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: urine

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c + Urinary Hemoglobin (24h)

Frequently asked questions

What does an abnormal HbA1c result mean?
An elevated HbA1c (typically above 6.5% on standard scales) suggests poor blood sugar control, which may require adjustments to diet, medication, or lifestyle. A positive urinary hemoglobin test could indicate hidden blood loss, prompting further evaluation by your doctor.
Can I fast before this test?
For HbA1c: No fasting is needed, as it measures long-term blood sugar. For urinary hemoglobin: No special preparation is required, but drinking water may help dilute urine for clearer results. Always follow your lab’s specific instructions.
How long will I need to collect urine for the 24-hour sample?
You’ll typically collect all urine for 24 hours, starting after a full void at midnight. Store samples in a refrigerator until delivery to the lab to preserve accuracy. Your doctor or lab will provide exact timing instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy