Red Blood Cell Morphology (with specific focus on red blood cell shape distribution)
This test examines the overall shape and distribution of red blood cells (RBCs) in your blood, which can help identify conditions affecting their structure.
["Understanding RBC shape helps diagnose blood disorders like anemia or inherited conditions."]
Key facts at a glance
- LOINC
- 11127-8
- Short code
- RBC Mar
- Synonyms
- RBC Mar
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why It Matters in Your Health
Red blood cells normally appear uniformly round and flexible. When they take on abnormal shapes—such as being too large, too small, or irregular—they may not function properly. This test helps detect whether your RBCs are deviating from normal shape, which can signal underlying health issues.
What to Expect Before the Test
No special preparation is needed for this test. It’s typically done as part of a routine blood draw. You may feel slight discomfort, but it’s usually brief. If you’re on blood-thinning medication, let your provider know before the test.
Common Conditions It Can Help Identify
Abnormal RBC shapes can point to conditions like hereditary spherocytosis, elliptocytosis, or conditions causing microcytic or macrocytic anemia. It may also help diagnose conditions affecting blood viscosity or clotting.
What the Results Mean
Results are usually reported as a qualitative assessment of RBC shape distribution rather than specific numeric values. Your healthcare provider will interpret the findings in the context of your overall health and symptoms.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: When This Test Is Important
Short name
RBC Shape Profile
Frequently asked questions
When would I need this test?
How often should I get this test?
Can lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy