Bromocresol Purple Protein Electrophoresis (Serum/Plasma)

What This Test Measures

Electrophoresis separates blood proteins based on size and charge. Bromocresol purple dye binds to proteins, allowing different protein fractions (albumin, alpha, beta, and gamma globulins) to be visualized. This helps detect shifts in protein composition that may not be visible in standard blood tests.

Why It’s Done

Doctors may order this test if you have symptoms like unexplained weight loss, fatigue, or swelling, or if lab results show abnormal protein levels. It’s also used to monitor conditions like multiple myeloma or to check for protein abnormalities in chronic diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The serum or plasma is then processed and analyzed in a lab using electrophoresis with bromocresol purple dye. Results are compared to standard patterns to identify any deviations.

What the Results Mean

Normal results show a typical distribution of proteins. Abnormal patterns may indicate high levels of certain proteins (e.g., monoclonal gammopathy) or low levels of others, which can signal underlying health problems like cancer or immune disorders.