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Autoantibody Profile to Autoantibodies Against Cardiac Proteins (Cardiac Autoantibody Screen)

Published: August 9, 2026Updated: August 17, 2026

This test measures certain antibodies your body may produce against proteins found in your heart. These antibodies can sometimes be linked to conditions affecting heart function.

Quick summary

["This screening helps identify potential heart-related autoimmune responses that may require further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
57842-7
Short code
RBC # Pcar Auto
Synonyms
RBC # Pcar Auto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of autoantibodies directed toward cardiac proteins, which may be associated with conditions like myocarditis, dilated cardiomyopathy, or other inflammatory heart diseases. It does not diagnose a specific condition but can flag a need for additional testing if abnormal results are found.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms like chest pain, fatigue, shortness of breath, or other signs of heart issues. It may also be used in research or monitoring for autoimmune-related heart conditions.

What to Expect Before the Test

No special preparation is typically needed. You may provide a blood sample, often drawn from a vein in your arm. If you are on blood thinners or have a history of bleeding disorders, let your provider know beforehand.

What to Expect During the Test

The blood sample is collected in a standard manner. The test involves analyzing the sample for specific autoantibodies using immunoassay methods. Results are usually reported as positive or negative for the presence of these antibodies.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cardiac Autoantibody Screen

Frequently asked questions

What Does a Positive Result Mean?
A positive result indicates the presence of autoantibodies against cardiac proteins, which may warrant further investigation by a healthcare provider to explore potential underlying causes, such as autoimmune heart disease.
Will This Test Help Diagnose My Condition?
This test is a screening tool and may not diagnose a specific condition alone. It can help identify potential autoimmune responses that may require additional diagnostic tests or consultations with a specialist, such as a cardiologist or rheumatologist.
Are There Any Risks or Side Effects?
The most common risk is a mild bruise or soreness at the injection site. Rarely, there may be a slight reaction to the blood draw, such as dizziness or fainting. If you experience severe pain or unusual symptoms, contact your healthcare provider immediately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy