Red Blood Cell Morphology Examination (Manual Count)
This test evaluates the shape, size, and overall health of red blood cells (RBCs) using a manual microscopic examination. It helps identify abnormalities that may indicate underlying conditions.
["This test assesses RBC shape and health to detect potential blood disorders."]
Key facts at a glance
- LOINC
- 795-5
- Short code
- RBC # Prt Manual
- Synonyms
- RBC # Prt Manual
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- manual-count
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors may order this test if you have symptoms like fatigue, pale skin, unusual bruising, or unexplained anemia. It’s also used to monitor conditions like sickle cell disease, thalassemia, or other inherited blood disorders. Sometimes, it’s part of a routine checkup or to investigate unexplained blood test results.
What to Expect During the Test
No special preparation is needed. A small blood sample is taken from a vein in your arm, similar to other blood tests. The sample is then examined under a microscope by a trained technician to assess RBC morphology.
What the Results Mean
The results describe the appearance of your RBCs, such as their size (MCV), shape (e.g., spherocytes, elliptocytes), and presence of any inclusions or abnormalities. While specific patterns can suggest certain conditions, results alone aren’t diagnostic. They’re usually interpreted alongside other clinical findings and tests.
Common Conditions Linked to RBC Morphology Abnormalities
Abnormal RBC shapes or counts can signal conditions like anemia (due to iron deficiency or other causes), hemolytic anemia (where RBCs are destroyed prematurely), or inherited disorders like spherocytosis or elliptocytosis. These findings may guide further testing or treatment.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Manual RBC Morphology Check
Frequently asked questions
What questions might you have about this test?
How often will I need this test?
You might feel a slight pinch or discomfort during the blood draw, but it’s usually over quickly. Most people don’t experience significant pain afterward. Your doctor or nurse will explain the process and provide details about any precautions.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy