Cerebrospinal Fluid (CSF) Red Blood Cell Count (Manual Cell Count)
This test measures the number of red blood cells in your cerebrospinal fluid, which is the fluid surrounding your brain and spinal cord. It helps assess for bleeding or trauma in the central nervous system.
["Red blood cells in CSF can signal bleeding or other issues in your brain or spinal cord."]
Key facts at a glance
- LOINC
- 76673-3
- Short code
- RBC tube1 # CSF Manual
- Synonyms
- RBC tube1 # CSF Manual
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- manual-count
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like severe headaches, neck stiffness, confusion, or neurological problems. It’s also used to monitor conditions like meningitis, subarachnoid hemorrhage, or traumatic brain injury.
What to Expect Before the Test
No special preparation is needed. You may have a lumbar puncture (spinal tap) to collect the CSF sample. This procedure involves inserting a needle into your lower back to draw fluid. You might feel pressure or discomfort, but it’s usually brief.
What the Test Results Mean
Normally, CSF contains very few red blood cells. Elevated counts may indicate bleeding in the brain or spinal cord, infections, or other conditions affecting the central nervous system. Your doctor will interpret results in the context of your symptoms and medical history.
Possible Causes of Abnormal Results
High red blood cell counts in CSF can be caused by traumatic lumbar puncture, bleeding disorders, subarachnoid hemorrhage, or inflammatory conditions like meningitis. Low counts may occur if the sample was contaminated or if the test was not performed correctly.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
CSF RBC Count
Frequently asked questions
What are the normal red blood cell counts in CSF?
How long does it take to get the results of this test?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy