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Cerebrospinal Fluid (CSF) Red Blood Cell Count (Manual Cell Count)

Published: August 9, 2026Updated: August 17, 2026

This test measures the number of red blood cells in your cerebrospinal fluid, which is the fluid surrounding your brain and spinal cord. It helps assess for bleeding or trauma in the central nervous system.

Quick summary

["Red blood cells in CSF can signal bleeding or other issues in your brain or spinal cord."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
76673-3
Short code
RBC tube1 # CSF Manual
Synonyms
RBC tube1 # CSF Manual
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
85041
SNOMED
900000000000003001
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like severe headaches, neck stiffness, confusion, or neurological problems. It’s also used to monitor conditions like meningitis, subarachnoid hemorrhage, or traumatic brain injury.

What to Expect Before the Test

No special preparation is needed. You may have a lumbar puncture (spinal tap) to collect the CSF sample. This procedure involves inserting a needle into your lower back to draw fluid. You might feel pressure or discomfort, but it’s usually brief.

What the Test Results Mean

Normally, CSF contains very few red blood cells. Elevated counts may indicate bleeding in the brain or spinal cord, infections, or other conditions affecting the central nervous system. Your doctor will interpret results in the context of your symptoms and medical history.

Possible Causes of Abnormal Results

High red blood cell counts in CSF can be caused by traumatic lumbar puncture, bleeding disorders, subarachnoid hemorrhage, or inflammatory conditions like meningitis. Low counts may occur if the sample was contaminated or if the test was not performed correctly.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: csf

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CSF RBC Count

Frequently asked questions

What are the normal red blood cell counts in CSF?
Normal red blood cell counts in CSF are generally very low, often below 10 per microliter. However, the exact range can vary based on the method used and clinical context. Your doctor will use these results alongside other tests and symptoms to guide diagnosis.
How long does it take to get the results of this test?
Results from this test are typically available within a few hours to a couple of days, depending on the lab’s processing time. Your healthcare provider will contact you once the results are ready.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor has specific instructions. Avoiding certain medications or foods may not be necessary unless directed by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy