Red Blood Cell Uptake Rate of Autoantibody Binding (Autoimmune Hemolytic Anemia Screening)
This test measures how red blood cells interact with certain antibodies that may cause them to be destroyed too quickly, a condition called autoimmune hemolytic anemia.
["Helps detect antibodies that could damage your red blood cells, guiding treatment for potential blood disorders."]
Key facts at a glance
- LOINC
- 798-9
- Short code
- RBC # Ur Auto
- Synonyms
- RBC # Ur Auto
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- automated-count
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
This test evaluates the binding capacity of red blood cells to specific autoantibodies, which are antibodies the body produces against its own cells. The method detects how quickly these antibodies attach to red blood cells, indicating potential autoimmune activity.
Why Might You Need This Test?
Your doctor may order this test if you have symptoms like fatigue, pale skin, or unexplained anemia, or if you have a history of autoimmune diseases. It helps identify whether your red blood cells are being destroyed by antibodies.
What Does a Positive Result Mean?
A positive result suggests increased autoantibody binding to red blood cells, which may signal an autoimmune condition causing hemolysis (destruction of red blood cells). Further testing and evaluation are needed to confirm diagnosis and determine treatment.
How Is This Test Performed?
Blood is drawn and mixed with a sample containing specific autoantibodies. The test measures how many red blood cells bind to these antibodies over time, reflecting their uptake rate.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test is critical for diagnosing autoimmune hemolytic anemia, a rare but serious condition where the immune system mistakenly attacks red blood cells. Early detection allows for timely intervention, such as adjusting medications or blood transfusions, to prevent severe complications like anemia or kidney failure.
Short name
Autoimmune Hemolytic Anemia Screening (Autoantibody Uptake Rate)
Frequently asked questions
What are the common symptoms of autoimmune hemolytic anemia?
How often is this test repeated if a positive result is found?
Can lifestyle changes help manage autoimmune hemolytic anemia?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy