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Vitamin D Binding Protein (DBP) - Serum

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of vitamin D binding protein, a protein in your blood that helps transport vitamin D and other substances.

Quick summary

["Understanding your vitamin D binding protein levels can help assess how well your body processes certain nutrients and vitamins."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
48051-7
Short code
RBC Vag Ql
Synonyms
RBC Vag Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if they suspect conditions related to how your body handles vitamin D, such as kidney disease, liver disease, or certain genetic disorders. It may also be part of a broader evaluation for metabolic or endocrine issues.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for a few hours before the test if it involves drawing blood, but this is not always the case. Always follow your healthcare provider’s instructions.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. The blood sample will be sent to a lab for analysis. The test usually takes a few minutes, and you may feel slight discomfort but no lasting effects.

What the Results Mean

Results are not typically interpreted alone. They are usually reviewed alongside other tests, symptoms, and medical history. Abnormal levels might indicate conditions affecting protein metabolism or vitamin D transport.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin D binding protein levels can be important in diagnosing or monitoring conditions like nephrotic syndrome, liver disease, or hereditary conditions affecting protein synthesis. It may also help assess how well vitamin D is being transported in the body, which can influence overall health and bone metabolism.

Short name

DBP

Frequently asked questions

What does a high level of vitamin D binding protein mean?
A high level might suggest conditions like nephrotic syndrome, liver disease, or certain genetic disorders that affect protein production or kidney function. It can also be influenced by factors like pregnancy or certain medications.
What does a low level of vitamin D binding protein mean?
A low level may indicate conditions such as severe kidney disease, malnutrition, or conditions that affect protein synthesis. It’s important to discuss these results with your healthcare provider to understand the full context.
Can diet or lifestyle affect vitamin D binding protein levels?
Diet and lifestyle factors like protein intake, kidney health, and certain medications may influence protein levels, including vitamin D binding protein. However, diet alone typically does not directly alter this specific protein’s concentration in the blood.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy