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Red Blood Cell (RBC) Redistribution Width (RBC RDW) by Automated Counting

Published: August 9, 2026Updated: August 17, 2026

This test measures the variation in size (redistribution width) of your red blood cells (RBCs) using an automated blood cell counter.

Quick summary

["RBC RDW helps doctors assess how evenly sized your red blood cells are, which can indicate certain blood disorders or health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
21000-5
Short code
RDW RBC Auto
Synonyms
RDW RBC Auto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does RBC RDW Measure?

RBC RDW evaluates the spread in size among your red blood cells. Normally, RBCs are relatively uniform in size, but certain conditions—such as anemia, iron deficiency, or other blood disorders—can cause a wider range of sizes. This test helps identify if your RBCs are consistently similar in size or if there is significant variation.

Why Might Your Doctor Order This Test?

Your doctor may request an RBC RDW test if they suspect conditions like anemia (low red blood cell count), iron deficiency, or other blood-related disorders. It can also be part of routine blood work to monitor chronic conditions or check for subtle changes in your blood health.

How Is This Test Performed?

This test uses a small sample of your blood, typically collected via a simple vein puncture. The blood is analyzed automatically by a machine that measures the size and shape of each red blood cell. No special preparation is needed, but fasting is not required.

What Are Common Uses of RBC RDW?

RBC RDW is often used alongside other blood tests to diagnose or monitor conditions such as megaloblastic anemia (caused by vitamin deficiencies like B12 or folate), thalassemia, or other inherited blood disorders. It can also help guide treatment decisions for iron deficiency or other blood-related issues.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated RBC RDW may suggest underlying issues like anemia, nutritional deficiencies, or chronic diseases. A normal RBC RDW does not rule out all blood disorders but can help narrow down potential causes when combined with other test results. Always discuss your results with your healthcare provider for personalized interpretation.

Short name

RBC RDW Auto

Frequently asked questions

What Does an Elevated RBC RDW Mean?
An elevated RBC RDW means there is a wider variation in the sizes of your red blood cells than usual. This can be a sign of conditions like anemia, vitamin deficiencies, or other blood disorders. Your doctor will review your full blood count and other test results to determine the best course of action.
What Does a Normal RBC RDW Indicate?
A normal RBC RDW suggests that your red blood cells are relatively uniform in size, which is typical in healthy individuals. However, it does not rule out all possible blood disorders, so your doctor may still recommend additional tests or monitoring based on your overall health and symptoms.
Does RBC RDW Require Special Preparation?
No special preparation is needed for this test. You can eat, drink, and go about your normal activities as usual. However, if you are taking certain medications or have a known condition, inform your healthcare provider before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy