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Red Blood Cell Distribution Width (RDW) Calculated from Mean Corpuscular Volume (MCV)

Published: August 9, 2026Updated: August 16, 2026

This test measures the variation in size of your red blood cells (RBCs). Healthy RBCs are generally similar in size, but an RDW test helps identify when they differ significantly, which can signal certain health conditions.

Quick summary

["Assessing RBC size consistency to detect potential blood disorders or nutritional deficiencies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76138-7
Short code
RDWr Bld Calc-Rto
Synonyms
RDWr Bld Calc-Rto
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
11.5
Ref high
14.5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
calculated
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why RDW Matters in Your Blood Health

RDW is calculated using your MCV (average RBC size) and other blood measurements. While not a standalone diagnostic test, it often accompanies complete blood count (CBC) panels. Your doctor may order it to investigate symptoms like fatigue, anemia, or unexplained bleeding.

How RDW Works in Your Blood Test

Your blood sample is analyzed to determine the range of RBC sizes. If most RBCs are uniform, your RDW will be low. If there’s a wide spread in sizes, your RDW will be higher. This variation can reflect underlying issues like iron deficiency, vitamin B12 or folate deficiency, or even early stages of certain blood disorders.

Common Reasons for RDW Testing

Doctors may order RDW testing when you have symptoms like pale skin, shortness of breath, unusual fatigue, or unexplained bleeding. It’s also used to monitor conditions like anemia, pernicious anemia, or other blood-related disorders where RBC size consistency is important.

What to Expect Before or After the Test

No special preparation is needed for this test. A simple blood draw from your arm is all that’s required. Results are typically available within a few days, depending on your lab. Your doctor will discuss any follow-up steps based on your results.

Reference range

Adult: 11.5-14.5%N/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: When RDW Points to Underlying Conditions

Short name

RDW (MCV-based)

Frequently asked questions

How long does it take to get RDW results?
RDW results are usually available within 2–5 business days, depending on your lab’s processing time. Your healthcare provider will contact you directly with the results and any next steps.
Can RDW results be affected by diet or medications?
Yes, certain foods (like red meat or iron supplements) and medications (e.g., blood thinners or chemotherapy) can influence RBC health and potentially your RDW. Always inform your doctor about any changes in your diet, supplements, or medications before testing.
Is RDW testing painful?
The blood draw for RDW testing is generally mild discomfort for a few seconds. Most people find it tolerable, and the area may feel slightly sore afterward. If you’re nervous, let your healthcare provider know—they can take precautions to minimize discomfort.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy