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Reaginic antibody (serum) – Atopy/Allergy Screen (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test detects specific antibodies (reagins) linked to allergic reactions, often used to assess potential sensitivity to environmental allergens.

Quick summary

["Helps identify possible allergic triggers that may cause symptoms like sneezing, itching, or skin reactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22460-0
Short code
Reagin Ab CSF-aCnc
Synonyms
Reagin Ab CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What This Test Measures

Reagins are a type of antibody produced by the immune system in response to certain allergens. This test measures their presence in your serum to determine if you may have an allergic reaction to specific substances, such as pollen, dust, or pet dander.

Why It’s Ordered

Your healthcare provider may recommend this test if you have symptoms like seasonal allergies, asthma, or chronic skin conditions that suggest an allergic reaction. It’s sometimes used alongside other allergy testing to guide treatment plans.

How the Test Works

A small blood sample is drawn, and the serum is tested for the presence of reagins using an immunoassay method. This detects if your immune system has produced antibodies against common allergens.

Sample Collection

A simple blood draw is performed in a clinic or lab. No special preparation is needed, but fasting may be advised depending on other tests ordered together.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results suggest a heightened immune response to allergens, which may confirm a diagnosis of allergic sensitivity. While not definitive for allergy diagnosis, it can support further testing (e.g., skin prick tests) or guide allergy management strategies.

Short name

Reaginic antibody test

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times.
What does a positive result mean?
A positive result indicates the presence of reagins, which may indicate an allergic tendency but does not specify the exact allergen. Follow-up testing may be needed to identify triggers.
Can I take allergy medication before the test?
Yes, you can take over-the-counter allergy medications (e.g., antihistamines) before the test, as they do not interfere with the test results. Avoid prescription allergy medications without consulting your provider first.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy