Reaginic antibody (serum) screening test
This test measures a type of antibody called a reagin, which may be present in certain allergic or autoimmune conditions. It is often used as part of a screening process.
["This screening helps identify potential allergic or autoimmune reactions that may require further evaluation."]
Key facts at a glance
- LOINC
- 22461-8
- Short code
- Reagin Ab Ser Ql
- Synonyms
- Reagin Ab Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is a Reaginic Antibody?
Reagins are a type of antibody that can be detected in the blood and are associated with certain allergic reactions or autoimmune conditions. Unlike other antibodies, reagins are not specific to a single antigen and can react with a wide range of substances. This test is typically used as a screening tool rather than a definitive diagnostic test.
Why Might Your Doctor Order This Test?
Your doctor may order this test if you have symptoms suggestive of an allergic reaction, such as hives, swelling, or respiratory issues, or if you have conditions like systemic lupus erythematosus (SLE) or other autoimmune diseases where antibody activity is suspected. It can also be part of a broader evaluation for unexplained symptoms.
What Does a Positive Result Mean?
A positive screening result for reagins does not always indicate a specific diagnosis. It may suggest an underlying allergic or autoimmune process that requires further testing, such as specific antibody testing or clinical correlation. Follow-up with your healthcare provider is essential to determine the next steps.
What Should You Expect During the Test?
The test involves drawing blood from a vein in your arm. You may feel a small pinch when the needle is inserted, but it usually doesn’t cause significant discomfort. The blood sample is then sent to a lab for analysis. Results are typically available within a few days.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Reagin antibody screening
Frequently asked questions
This test is primarily used as a screening tool to identify patients who may have an increased likelihood of certain allergic or autoimmune conditions. It does not replace clinical judgment or additional diagnostic testing. If results are positive, further evaluation with specific antibody tests or other diagnostic procedures may be recommended to narrow down the cause of symptoms.
If your doctor recommends repeating this test, it can be done as needed based on your symptoms or clinical situation. However, repeated testing should always be discussed with your healthcare provider to ensure it aligns with your diagnosis and treatment plan.
Can lifestyle changes or medications affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy