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Recoverin Immunoblot (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to recoverin, a protein found in certain eye conditions like retinitis pigmentosa or other inherited retinal diseases. It helps diagnose or monitor conditions affecting vision.

Quick summary

This test checks for specific antibodies linked to rare genetic eye disorders.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
83003-4
Short code
Recoverin IgG SerPl Ql Line blot
Synonyms
Recoverin IgG SerPl Ql Line blot
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
line-blot
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may recommend this test if you have symptoms like vision changes, night blindness, or a family history of inherited retinal diseases. It’s often used when other tests (like genetic screening) are inconclusive or to confirm suspected conditions.

What to Expect During the Test

A blood sample is drawn from a vein in your arm. The serum is then analyzed using an immunoblot technique to identify antibodies against recoverin. This process may take several hours in the lab.

Sample Collection and Preparation

The test uses serum from your blood, which is separated from blood cells. This sample is processed and tested for recoverin-specific antibodies without further manipulation.

What the Results Mean

Positive results indicate the presence of antibodies against recoverin, which may suggest an autoimmune or inflammatory response linked to retinal diseases. Negative results mean no detectable antibodies were found in this test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is primarily used to support a diagnosis of autoimmune-related retinal disorders, such as those involving recoverin, which can cause progressive vision loss. It may also help differentiate between genetic and autoimmune causes of similar symptoms. Results should be interpreted alongside clinical findings and other diagnostic tests.

Short name

Recoverin Antibody Screening/Confirmation

Frequently asked questions

What causes recoverin antibodies to appear in the blood?
Recoverin antibodies may develop due to autoimmune reactions targeting retinal proteins, often seen in conditions like retinitis pigmentosa or other inherited retinal dystrophies. They can also arise from exposure to environmental factors or certain medications. Your doctor will consider your symptoms, medical history, and other test results to determine the cause.
How long does it take to get results from this test?
Test results are typically available within 3 to 7 business days, depending on lab processing times. Your healthcare provider will contact you once results are ready.
Can this test be done at home?
No, this test requires a blood sample collected by a healthcare professional. You’ll need to schedule an appointment with a lab or doctor for the procedure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy