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Granulocyte Count (Absolute Neutrophil Count, ANC)

Published: August 9, 2026Updated: August 17, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections and inflammation.

Quick summary

["Neutrophils are key defenders against bacterial infections; low or high levels may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102819-0
Short code
Red Snapper IgG RAST
Synonyms
Red Snapper IgG RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to diagnose or monitor conditions like infections, certain cancers (e.g., leukemia), immune disorders, or to check how your body responds to treatments that affect white blood cells.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your vein (usually in your arm) to draw blood. It usually takes a few minutes, and you may feel a brief pinch.

What the Test Results Mean

Results are expressed as the count of neutrophils per microliter (µL) of blood. Abnormal levels (either too high or too low) can indicate infections, immune system issues, or other health problems.

Common Conditions Affecting Neutrophil Levels

Low neutrophil counts (neutropenia) may be linked to infections, autoimmune diseases, or medications that suppress the bone marrow. High neutrophil counts (neutrophilia) can occur with infections, stress, or certain inflammatory conditions.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Neutrophils are the body’s primary responders to bacterial infections. Low counts increase infection risk, while high counts may signal acute infection, inflammation, or stress responses. This test helps guide treatment for infections, cancer, or immune disorders.

Short name

ANC

Frequently asked questions

What causes my neutrophil count to be low?
Low neutrophil counts can result from infections, certain medications (like chemotherapy), autoimmune diseases, or genetic conditions. If you’ve been taking new medications or have symptoms like frequent infections, discuss this with your doctor.
How often should I get this test?
Your doctor will determine the frequency based on your health condition. Regular monitoring may be needed if you have chronic illnesses like cancer, autoimmune disorders, or if you’re on treatments that affect white blood cells.
Can lifestyle changes affect neutrophil counts?
While diet and hydration support overall immune function, neutrophil counts are primarily influenced by infections, medications, and underlying health conditions. Your doctor will focus on your specific situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy