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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring how well your kidneys remove waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7368-4
Short code
Red top grass BasoBnd Ab Qn
Synonyms
Red top grass BasoBnd Ab Qn
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
lhr
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is naturally filtered out by your kidneys. High levels may indicate poor kidney function, while low levels could suggest overhydration or muscle loss. This test is often used alongside other kidney function tests to diagnose or monitor conditions like chronic kidney disease.

How the Test Works

A small blood sample is taken from your arm and sent to a lab. The lab uses a specialized method (such as enzymatic or nephelometric techniques) to measure the creatinine concentration in your serum or plasma.

What to Expect Before the Test

You can eat and drink normally before the test. Avoid excessive protein intake 24 hours before if your doctor advises it, as it may affect results. If you have diabetes or are on certain medications, discuss this with your healthcare provider to ensure accurate results.

What to Expect During the Test

The test involves a quick, painless blood draw from your vein. You may feel a slight pinch, but it usually takes only a few minutes. You can resume your usual activities immediately afterward.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

High creatinine levels may signal kidney problems, including chronic kidney disease, acute kidney injury, or conditions that reduce blood flow to the kidneys. Low levels might suggest dehydration, muscle wasting, or errors in lab processing. Regular monitoring of creatinine levels is essential for managing kidney health and other related conditions.
Your creatinine test results will be reviewed by your healthcare provider in the context of your overall health and other tests. If your levels are abnormal, further evaluation may be needed to determine the cause and appropriate treatment.
How often should I get this test?
The frequency depends on your health status. If you have kidney disease, diabetes, or high blood pressure, your doctor may recommend testing every few months or annually. If you’re generally healthy, it might be done less often, such as during routine check-ups or if you have symptoms like fatigue, swelling, or changes in urine.
Can diet or medications affect my creatinine test results?
Yes, certain foods (like high-protein diets) and medications (such as NSAIDs or certain diuretics) can influence creatinine levels. Always inform your doctor about any changes in diet, supplements, or medications before your test to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy