Skip to content

Renin Activity in Plasma (24-Hour Urinary Excretion)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of renin, an enzyme produced by your kidneys, that appears in your urine over a 24-hour period. It helps assess kidney function and blood pressure regulation.

Quick summary

["Renin helps control blood pressure and fluid balance; abnormal levels may indicate kidney or cardiovascular issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81432-7
Short code
Reg deg MV Angio
Synonyms
Reg deg MV Angio
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
angiography
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like high blood pressure, kidney problems, or signs of fluid imbalance. It can also help diagnose conditions like primary aldosteronism or certain types of kidney disease.

What to Expect Before the Test

No special preparation is needed, but you may be asked to collect a full 24-hour urine sample. Follow your doctor’s instructions carefully to ensure accurate results.

How the Test Works

Your urine sample is analyzed in a lab to measure renin levels. The test detects the enzyme’s presence and concentration over the full day to evaluate kidney function and hormonal balance.

Possible Results and Their Meaning

Higher-than-normal renin levels may suggest conditions like kidney disease or certain hormonal imbalances. Lower-than-normal levels could indicate conditions affecting kidney function or blood pressure regulation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: What This Test Can Reveal

Short name

24-Hour Urinary Renin

Frequently asked questions

What could cause abnormal renin levels?
Abnormal renin levels can be linked to kidney disorders (e.g., renal artery stenosis), hormonal imbalances (e.g., primary hyperaldosteronism), or conditions affecting blood pressure regulation. Always discuss results with your healthcare provider.
How often should I get this test?
Your doctor will determine the frequency based on your symptoms, medical history, and other test results. Follow their guidance for follow-up testing if needed.
Can diet or medications affect this test?
Yes, certain medications (e.g., blood pressure drugs) or dietary changes (e.g., salt intake) may influence renin levels. Inform your doctor about all medications and supplements you take before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy