Skip to content

Serum Immunoglobulin Profile (Qualitative Mix Screening for Multiple Immunoglobulins)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence or absence of key antibodies (immunoglobulins) in your blood, including IgG, IgA, IgM, and sometimes IgE, to help identify immune system responses or deficiencies.

Quick summary

["This screening helps detect potential immune-related conditions or reactions to allergens or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15256-1
Short code
Region Allerg Mix1 IgE Ql
Synonyms
Region Allerg Mix1 IgE Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test evaluates multiple immunoglobulins (IgG, IgA, IgM, and potentially IgE) using a qualitative immunoassay method. It does not provide exact quantities but identifies whether these antibodies are present or absent in your serum.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent infections, unusual allergic reactions, immune system disorders, or if you’re being evaluated for conditions like primary immunodeficiency, autoimmune diseases, or certain allergies.

Common Conditions Linked to This Test

Results may help diagnose conditions such as hypogammaglobulinemia (low antibody levels), autoimmune diseases, or allergic reactions. It can also support monitoring for immune-related treatments.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm for a blood draw, similar to other routine blood tests. Wear comfortable clothing if you’re having the draw at a clinic.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Ig Mix Screen (Serum)

Frequently asked questions

What does a positive or negative result mean?
A positive result (detected antibodies) indicates the presence of those immunoglobulins, which may suggest an immune response to infection, allergies, or an autoimmune condition. A negative result means those specific antibodies were not detected in this sample, which may warrant further testing.
How often should I get this test?
Frequency depends on your health needs. Your doctor may recommend this test once or periodically if you have a known condition affecting your immune system or allergies. Follow-up may include additional tests or monitoring.
Can I eat or drink before this test?
Yes, you can eat and drink normally before this test. No fasting is required, unlike some other blood tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy