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Regional Allergen Mix 1-Specific IgE, Serum — Radioallergosorbent Test (RAST)

Published: August 9, 2026Updated: August 17, 2026

A blood test that screens for IgE antibodies to a group of common allergens found in a specific geographic region.

Quick summary

["A positive result suggests allergy sensitization, but symptoms and medical history are needed to determine whether the allergens cause your symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
82102-5
Short code
Region Allerg Mix1 IgE RAST
Synonyms
Region Allerg Mix1 IgE RAST
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures allergen-specific IgE antibodies in a blood sample using a radioallergosorbent test, or RAST. It screens for immune sensitization to allergens included in a regional mixture, whose contents may vary by the laboratory and geographic area.

Why might I need this test?

It may be used to help identify possible triggers of allergic rhinitis, wheezing, hives, or other allergic symptoms when the cause is unclear. The panel can be a useful starting point before more specific allergy testing is considered.

How is the test performed?

A blood sample is collected and tested in a laboratory for IgE antibodies against the allergens in the regional mixture. The laboratory may report each allergen separately or provide a combined result, depending on the test used.

How do I prepare for the test?

Fasting is usually not required. Tell your healthcare professional about your allergies, current symptoms, allergy treatments, and any recent immunotherapy, because these details may affect how the results are interpreted.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detectable IgE to one or more allergens indicates sensitization and may help explain symptoms related to exposure. However, a positive result does not by itself prove that the allergens cause your symptoms, and test strength does not reliably predict reaction severity. Results should be interpreted with your medical history and, when needed, additional allergy testing.

Short name

Regional Allergen Mix 1 IgE (RAST)

Frequently asked questions

Does a positive RAST mean I am allergic?
It means your immune system has produced IgE antibodies to one or more tested allergens. Some people have sensitization without symptoms, so a clinician should interpret the result alongside your history and examination.
What allergens are included in the regional mix?
The allergens can vary by laboratory and geographic region. Common mixtures may include pollens, molds, dust mites, or animal allergens; ask the laboratory for the specific panel contents.
Should I stop taking allergy medicine before the test?
Do not stop prescribed medicines unless your clinician advises you to. Although antihistamines usually do not affect serum-specific IgE testing, your clinician can provide preparation instructions for your situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy