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Regional Allergen Mix 2–Specific IgE, Qualitative

Published: August 9, 2026Updated: August 16, 2026

A blood test that detects IgE antibodies to a mixture of allergens common in a particular geographic region, helping identify possible allergy triggers.

Quick summary

["A positive result indicates possible IgE-mediated sensitization to one or more allergens in the regional mixture, but must be interpreted alongside symptoms and other allergy testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82105-8
Short code
Region Allerg Mix2 IgE Qn
Synonyms
Region Allerg Mix2 IgE Qn
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures allergen-specific IgE antibodies in your blood. It uses a mixture of environmental allergens associated with a particular region rather than testing one individual allergen at a time.

Why might I need this test?

You may need this test if you have sneezing, congestion, wheezing, cough, skin rash, or other symptoms that seem related to exposure to regional allergens. Your clinician may also use it when symptoms suggest an allergy but the relevant trigger is unclear.

How is the test performed?

A blood sample is collected and tested for IgE antibodies against the allergens in the regional mixture. Because several allergens are assessed together, the result may need to be followed with testing for individual allergens.

How do I prepare for the test?

No fasting is usually required. Tell your clinician about any recent allergy shots, biologic immunotherapy, immune-system conditions, or immunosuppressive medicines, because these may affect interpretation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Regional Allergen Mix 2 IgE

Frequently asked questions

Does a positive result mean I am definitely allergic?
No. It indicates sensitization and may identify a likely trigger, but your clinician must interpret it with your symptoms and other findings.
Can this test tell me which specific allergen is causing my symptoms?
Not always. Because the laboratory uses an allergen mixture, follow-up testing for individual allergens may be needed.
Do I need to stop allergy medicines before the test?
Do not stop prescribed medicines without medical advice. Let your clinician know about allergy shots, biologic treatments, and immune-affecting medicines before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy