Skip to content

Regional Allergen Mix 4-Specific IgE (RAST), Serum

Published: August 9, 2026Updated: August 17, 2026

A blood test that measures IgE antibodies to a group of environmental allergens commonly encountered in a particular region.

Quick summary

["Elevated allergen-specific IgE may indicate an allergy to one or more allergens included in the panel."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
82108-2
Short code
Region Allerg Mix4 IgE RAST
Synonyms
Region Allerg Mix4 IgE RAST
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures allergen-specific IgE antibodies in your blood. It is sometimes called a RAST test and evaluates your immune response to a regional group of environmental allergens.

Why might I need this test?

Your clinician may order it to help identify possible triggers of allergy symptoms such as sneezing, congestion, wheezing, or itchy eyes. The results may guide allergy testing, avoidance, or treatment decisions.

How is the test performed?

A blood sample is drawn and analyzed for IgE antibodies to the allergens in the regional mix. The laboratory may report results for individual allergens or for the allergens as a group, depending on the panel used.

How do I prepare for the test?

No special preparation is usually needed. Tell your clinician about current antihistamine or other allergy medicines, because some treatments can affect test results.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated result suggests that your immune system has produced IgE antibodies to the tested allergen, but it does not by itself prove that the allergen causes your symptoms. Results should be interpreted with your exposure history, symptoms, and other allergy tests by your clinician.

Short name

Regional Allergen Mix 4 IgE

Frequently asked questions

Does this test diagnose an allergy?
It can support an allergy diagnosis by detecting allergen-specific IgE, but a positive result must be considered alongside your symptoms and exposure history.
What allergens are included in Regional Allergen Mix 4?
The exact allergens can vary by laboratory and regional testing panel. Ask the laboratory or your clinician for the specific allergen list included in your report.
Should I stop taking allergy medicine before the test?
Do not stop prescribed medicines unless your clinician instructs you to do so. Some antihistamines and other allergy treatments may affect the results, so discuss all current medicines before testing.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy