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Total Serum Immunoglobulin E (IgE) Level with Specific Allergen Sensitization Profile

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s immune response to common allergens, helping identify specific triggers for allergic reactions like hay fever, asthma, or skin rashes.

Quick summary

["Assists doctors in diagnosing and managing allergy-related symptoms by pinpointing which allergens may cause reactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51526-2
Short code
Region Allerg Mix5 IgE Ql
Synonyms
Region Allerg Mix5 IgE Ql
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects levels of Immunoglobulin E (IgE), a protein your immune system produces in response to allergens. It also evaluates sensitization to specific allergens (e.g., pollen, dust mites, pet dander, foods) via skin prick or blood-based methods. Results help link symptoms to potential triggers.

Why It’s Done

Your doctor may recommend this test if you experience symptoms like sneezing, itching, hives, wheezing, or digestive issues that suggest allergies. It’s often used alongside allergy skin tests or blood tests for confirmation.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The sample is processed to separate serum (liquid part of blood) for testing. No special preparation is needed, but fasting may be advised depending on the specific allergens being tested.

Test Results Interpretation

Results show your baseline IgE level and whether your body is sensitized to specific allergens. Elevated IgE or positive sensitization to certain allergens may indicate an allergic reaction risk, but they don’t confirm a diagnosis alone. Results are used alongside clinical findings and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Allergy Panel

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on the lab and testing complexity. Follow-up with your healthcare provider to discuss findings.
What does a ‘positive’ result mean?
A ‘positive’ result means your immune system has detected sensitization to specific allergens, which may correlate with allergic symptoms. However, false positives can occur, so results are interpreted alongside your medical history and symptoms.
Can I avoid allergens based solely on test results?
While test results help identify potential allergens, they don’t guarantee a reaction will occur. Always consult your doctor before making changes to your diet, environment, or medications based on test results alone.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy