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Regional Allergen Mix 5–Specific IgE (RAST), Serum

Published: August 9, 2026Updated: August 17, 2026

A blood test that measures IgE antibodies to a regional group of common allergens. It may help identify which allergens are associated with allergy symptoms.

Quick summary

["This test can help link allergy symptoms to specific regional allergens by measuring IgE antibodies in blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
82112-4
Short code
Region Allerg Mix5 IgE RAST
Synonyms
Region Allerg Mix5 IgE RAST
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is an allergy blood test known as a RAST test. It measures allergen-specific IgE antibodies against a group of allergens commonly found in a particular geographic region. The exact allergens included can vary by laboratory.

Why might I need this test?

Your clinician may order this test to help evaluate sneezing, wheezing, congestion, hives, or other possible allergy symptoms. It can be useful when skin testing is difficult, cannot be performed safely, or has not provided enough information.

How is the test performed?

A blood sample is collected and analyzed in the laboratory for IgE antibodies to the allergens in the regional mix. The results are usually reported as positive or negative for each included allergen.

How do I prepare for the test?

No special preparation is usually required for this blood test. Tell your clinician about any allergy medicines or treatments you are using, and do not stop them without medical advice.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result shows that IgE antibodies to one or more included allergens are present, but it does not by itself prove that the allergen causes your symptoms. Results should be interpreted with your symptoms, medical history, exposure patterns, and any other allergy testing your clinician recommends.

Short name

Regional Allergen Mix 5 IgE

Frequently asked questions

Does a positive result mean I am allergic to every allergen in the panel?
No. Each allergen is evaluated separately. A positive result indicates sensitization to that particular allergen, while your clinician considers whether it fits your symptoms and exposure history.
Can this test be used when I am taking antihistamines?
The test can generally be performed while taking allergy medicines. Discuss your medications with your clinician so the results can be interpreted in the context of your treatment.
Is a blood allergy test the same as a skin-prick test?
No. A RAST test measures allergen-specific IgE in blood, while skin-prick testing observes a skin reaction after allergens are introduced. They can provide different information and are interpreted together with your clinical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy