Plasma Renin Activity (measured via renin substrate conversion to angiotensin I)
This test measures how much renin your kidneys produce. Renin is an enzyme that plays a key role in regulating your blood pressure and fluid balance.
["Renin activity helps assess kidney function and blood pressure regulation."]
Key facts at a glance
- LOINC
- 56577-0
- Short code
- Renin 1.5h p chal Plas-cCnc
- Synonyms
- Renin 1.5h p chal Plas-cCnc
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Renin Activity Testing Used For?
Doctors may order this test to evaluate kidney function, especially if you have symptoms like high blood pressure, kidney disease, or conditions affecting fluid balance. It can also help diagnose or monitor conditions like primary aldosteronism or certain types of hypertension.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The sample is processed to measure renin activity, which is then compared to standard levels to help determine if your kidneys are functioning normally or if there may be an underlying issue.
What Does the Test Result Mean?
Results may indicate whether your kidneys are producing too much or too little renin. Elevated levels might suggest conditions like kidney disease or certain hormonal imbalances, while lower levels could point to other health concerns. Your doctor will interpret the result in the context of your overall health and symptoms.
Common Conditions Monitored With This Test
This test is often used alongside other blood pressure or kidney function tests to diagnose or manage conditions such as hypertension, kidney disease, or hormonal imbalances affecting blood pressure regulation.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Renin Activity
Frequently asked questions
Why might my doctor request this test?
How long does it take to get my test results?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy