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Plasma Renin Activity (measured as renin concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the activity of renin, an enzyme produced by your kidneys that helps regulate blood pressure and fluid balance.

Quick summary

["Renin activity helps assess kidney function and blood pressure regulation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
13867-7
Short code
Renin 1h p 25 mg Cpl PO Plas-cCnc
Synonyms
Renin 1h p 25 mg Cpl PO Plas-cCnc
Category
coagulation
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
0
Ref high
2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like high blood pressure, kidney problems, or conditions affecting fluid balance. It can also help diagnose or monitor certain hormonal or kidney-related disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to avoid certain medications or foods for a few days before testing. Your doctor will provide specific instructions if applicable.

What the Test Involves

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to measure renin activity levels in your plasma.

What the Results Mean

Higher-than-normal levels may indicate conditions like primary aldosteronism or kidney disease, while lower-than-normal levels could suggest conditions affecting hormone regulation or kidney function.

Reference range

NCBI: SCC <2.0 ng/mLN/A

Specimen: plasma

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Renin Activity plays a key role in maintaining blood pressure and fluid balance. Abnormal levels can signal underlying kidney disorders, hormonal imbalances, or conditions affecting cardiovascular health.

Short name

Renin Activity

Frequently asked questions

What causes abnormal renin activity levels?
Abnormal renin activity may be caused by kidney diseases, certain hormonal imbalances, medications affecting blood pressure or fluid balance, or conditions like primary aldosteronism or chronic kidney disease.
How long does it take to get results?
Test results are typically available within a few days to a week, depending on your lab’s processing time. Your doctor will discuss the results with you during your follow-up visit.
Can diet or medications affect this test?
Yes, certain medications (like diuretics or blood pressure drugs) and dietary changes (such as sodium intake) can influence renin levels. Follow your doctor’s instructions regarding any temporary adjustments before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy