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Angiotensinogen (Serum) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of angiotensinogen, a protein in your blood that plays a role in regulating blood pressure and fluid balance. It may be checked to help diagnose or monitor conditions affecting these systems.

Quick summary

["Angiotensinogen helps control blood pressure and fluid balance; levels can signal kidney or liver issues or genetic conditions like hyperangiotensinemia."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56580-4
Short code
Renin 20M p chal Plas-cCnc
Synonyms
Renin 20M p chal Plas-cCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84075
SNOMED
27550007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like high blood pressure, swelling, or if you have a family history of conditions affecting blood pressure regulation. It can also be part of evaluating kidney or liver function, or certain genetic disorders.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a larger blood panel. Bring any medications you’re taking to your appointment.

How the Test Is Performed

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab for analysis using an immunoassay method to measure the protein concentration.

What the Results Mean

Results are compared to a reference range specific to your lab. Abnormal levels may indicate conditions like liver disease, kidney problems, or genetic disorders affecting protein production.

Reference range

Adult: 44-147 U/LN/A

Specimen: plasma

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Angiotensinogen Level

Frequently asked questions

What might cause abnormal results?
Elevated levels may suggest liver disease, certain genetic disorders (e.g., hyperangiotensinemia), or conditions that increase angiotensinogen production. Low levels could indicate liver dysfunction or hereditary conditions.
How do I interpret my results?
Your healthcare provider will discuss your results in detail, considering your medical history, symptoms, and other test results. Reference ranges vary by lab, so they’ll help clarify what your specific result means for you.
Can I fast before this test?
Most often, fasting is not required unless this test is part of a broader panel. Always follow your provider’s instructions, as fasting rules may differ depending on the test’s context.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy