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Plasma Renin Activity (Renin Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of renin in your blood. Renin is an enzyme that plays a key role in regulating blood pressure and fluid balance.

Quick summary

["Renin helps control how much fluid stays in your body and blood pressure levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12900-7
Short code
Renin sp2 p chal Plas-cCnc
Synonyms
Renin sp2 p chal Plas-cCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84075
SNOMED
27550007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order this test if you have symptoms like high blood pressure, kidney problems, or conditions affecting your body’s ability to regulate fluid and salt, such as heart failure or certain hormonal disorders.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to avoid certain medications or foods for a short time before the test, depending on your doctor’s instructions. Bring any medications you’re currently taking to your appointment.

How the Test Is Performed

A blood sample is drawn from a vein, usually in your arm, using a small needle. You may feel a slight sting when the needle goes in, but the procedure is quick and typically doesn’t cause discomfort afterward.

What the Results Mean

Results can help identify whether your body is producing too much or too little renin, which may indicate underlying health conditions like hypertension, kidney disease, or hormonal imbalances.

Reference range

Adult: 44-147 U/LN/A

Specimen: plasma

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Renin Level

Frequently asked questions

How Often Is This Test Done?
This test is typically done as part of a diagnostic evaluation, often only once or a few times depending on your symptoms and medical history. It’s not a routine screening test for most people.
What Are Common Causes of Abnormal Results?
Abnormal renin levels can be caused by conditions like kidney disease, heart failure, certain medications (such as diuretics or beta-blockers), or hormonal imbalances. Your doctor will discuss your results and any potential causes with you.
Can Diet or Medications Affect This Test?
Yes, certain foods, medications, and lifestyle factors can influence renin levels. For example, high-sodium diets or medications like ACE inhibitors or angiotensin II receptor blockers may affect results. Always follow your doctor’s specific instructions regarding diet or medication adjustments before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy