Renin to Uric Acid Ratio in Plasma (24-Hour Collection)
This test measures the ratio of renin—a hormone involved in blood pressure regulation—to uric acid in your plasma over 24 hours. It helps assess kidney function and potential kidney-related conditions.
["This ratio can help identify kidney issues or how your kidneys handle blood pressure regulation."]
Key facts at a glance
- LOINC
- 56976-4
- Short code
- Renin upr+1h p chal Plas-mCnc
- Synonyms
- Renin upr+1h p chal Plas-mCnc
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like high blood pressure, kidney problems, or if they suspect conditions like primary hyperaldosteronism, chronic kidney disease, or other kidney-related disorders. It can also help monitor kidney function in certain chronic conditions.
What to Expect Before the Test
You’ll need to collect a 24-hour urine sample starting after your first morning urine void. Follow your healthcare provider’s instructions carefully to ensure accurate results. Avoid certain medications or foods that could affect uric acid levels.
What the Test Measures
Renin is measured in plasma, while uric acid is measured in the collected urine over 24 hours. The ratio helps evaluate how your kidneys process these substances, which can indicate kidney function and blood pressure regulation.
Possible Results and Interpretation
Results are typically interpreted by your doctor in relation to your medical history and other test results. Abnormal ratios may suggest kidney dysfunction, hormonal imbalances, or other underlying health issues.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is particularly useful for diagnosing or monitoring conditions affecting kidney function, blood pressure, or hormone regulation. Elevated or low ratios may point to conditions like chronic kidney disease, hyperaldosteronism, or other metabolic disorders.
Short name
24-Hour Renin/Uric Acid Ratio
Frequently asked questions
What does a high or low ratio mean?
How often will I need this test?
Can I eat or drink anything before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy