Renin to Uric Acid Ratio in Plasma (24-Hour Collection)
This test measures the ratio of renin (an enzyme involved in blood pressure regulation) to uric acid (a waste product from the body’s metabolism) in your plasma over a 24-hour period. It helps assess how well your kidneys are managing fluid balance and blood pressure.
["Helps evaluate kidney function and blood pressure regulation over time."]
Key facts at a glance
- LOINC
- 56975-6
- Short code
- Renin upr+30M p chal Plas-mCnc
- Synonyms
- Renin upr+30M p chal Plas-mCnc
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like high blood pressure, kidney issues, or conditions affecting fluid balance. It can also help diagnose or monitor certain kidney-related disorders or kidney disease progression.
What to Expect Before the Test
You’ll need to collect urine for 24 hours, starting and ending with your first morning urine. Store all urine samples in a refrigerator until you return them to the lab. Follow your doctor’s instructions carefully to ensure accurate results.
How the Test Works
Your urine is analyzed for both renin and uric acid levels. The test calculates the ratio of these two substances to assess kidney function and how your body regulates fluid and blood pressure.
Possible Results and Interpretation
Results are typically reported as a ratio, but they’re interpreted by your healthcare provider based on your medical history and symptoms. Abnormal ratios may indicate kidney problems, fluid imbalances, or other conditions affecting blood pressure regulation.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Renin/Uric Acid Ratio
Frequently asked questions
What does a high or low ratio mean?
How often will I need this test?
Can I drink fluids before or during the 24-hour urine collection?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy