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Renin concentration in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of renin, an enzyme produced by your kidneys, in your plasma. Renin plays a key role in regulating blood pressure and fluid balance.

Quick summary

["Renin helps control your body’s blood pressure and fluid levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47883-4
Short code
Renin upr Plas-mCnc
Synonyms
Renin upr Plas-mCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to evaluate kidney function, check for conditions affecting blood pressure like primary aldosteronism, or assess how well your kidneys are responding to certain medications. It can also help diagnose or monitor conditions such as hypertension (high blood pressure) or heart failure.

What Does It Measure?

Renin is released by the kidneys in response to low blood pressure or low blood volume. High levels may indicate conditions like kidney disease or certain hormonal imbalances, while low levels might suggest conditions like heart failure or medications that affect kidney function.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate the plasma, which is sent to a lab for measurement. The test measures renin’s concentration in the plasma, typically expressed in units per liter or nanograms per liter.

What Are Possible Results?

Results are not provided with specific reference ranges as they can vary based on individual health, medications, and test conditions. Your doctor will interpret the results in relation to your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Plasma renin level

Frequently asked questions

What Might Cause High or Low Renin Levels?
High renin levels may be linked to conditions such as kidney disease, primary aldosteronism, or certain medications that affect blood pressure. Low renin levels could be associated with heart failure, kidney failure, or conditions that reduce kidney function.
How Does This Test Fit Into My Health Plan?
This test is often used alongside other blood pressure and kidney function tests to create a full picture of your health. Your doctor may use these results to adjust medications, recommend lifestyle changes, or monitor chronic conditions.
What Are Common Side Effects or Risks?
There are generally no serious side effects from a simple blood draw. You might experience mild discomfort or bruising at the site, but these are uncommon. Rarely, there could be a slight reaction to the needle insertion.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy