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Mycoplasma pneumoniae Antibody, Serum (Qualitative or Quantitative Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to *Mycoplasma pneumoniae*, a common cause of respiratory infections like pneumonia and bronchitis.

Quick summary

["Helps diagnose respiratory infections caused by *Mycoplasma pneumoniae* through antibody detection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
686-6
Short code
Resp Mycoplasma Spec Cult
Synonyms
Resp Mycoplasma Spec Cult
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like persistent cough, fever, or chest pain that suggest a bacterial infection, especially if other tests (like a chest X-ray or culture) are inconclusive. It’s often used when *Mycoplasma pneumoniae* is suspected but not confirmed by other methods.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, usually in your arm. You may feel a slight pinch, but it’s quick and typically done in a clinic or lab.

What the Test Results Mean

Results are qualitative (positive/negative) or quantitative (measuring antibody levels). A positive result means your immune system has detected *Mycoplasma pneumoniae* antibodies, suggesting past or current infection. A negative result means no detectable antibodies were found, but this doesn’t rule out infection if testing was done too early.

Possible Side Effects

The most common side effect is mild bruising, redness, or soreness at the injection site. Rarely, you might experience dizziness or a slight headache. If you experience severe pain or swelling, contact your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Mycoplasma pneumoniae antibodies

Frequently asked questions

This test plays a key role in diagnosing atypical pneumonia or respiratory illnesses where *Mycoplasma pneumoniae* is suspected. It’s particularly useful in cases where traditional bacterial cultures are negative, helping guide treatment with appropriate antibiotics (like azithromycin or doxycycline).
What does a positive result mean?
A positive result indicates your body has produced antibodies against *Mycoplasma pneumoniae*, which may mean you’ve had an infection in the past or are currently infected. However, antibody levels can vary, so additional testing or clinical correlation may be needed for diagnosis.
How soon will I get my results?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss them with you during your follow-up visit.
Yes, this test is generally safe during pregnancy or breastfeeding. However, always discuss your specific situation with your healthcare provider to ensure it’s appropriate for your needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy