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Mycoplasma pneumoniae Antibody, Serum (Qualitative Detection of IgG and IgM)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies against *Mycoplasma pneumoniae*, a common cause of respiratory infections like pneumonia and bronchitis in adults and children.

Quick summary

["Helps diagnose infections caused by *Mycoplasma pneumoniae* when symptoms like cough or fever persist."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
684-1
Short code
Resp Mycoplasma Spt Cult
Synonyms
Resp Mycoplasma Spt Cult
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects two types of antibodies—IgG (long-term immunity markers) and IgM (early infection markers)—against *Mycoplasma pneumoniae*. These antibodies develop in response to the bacteria and can indicate past or current infection. Results are reported qualitatively (positive/negative) rather than with numeric values.

Why It’s Ordered

Your doctor may order this test if you have unexplained respiratory symptoms (e.g., persistent cough, fever) that don’t improve with typical antibiotics, or if you’ve been exposed to someone with a suspected *Mycoplasma pneumoniae* infection.

What to Expect Before the Test

No special preparation is needed. A blood sample is drawn from a vein, usually in your arm. The process takes about 5 minutes, and you may feel slight discomfort for a few seconds.

What the Results Mean

Positive results (IgG or IgM) suggest recent or past infection. A positive IgM result alone may indicate an acute infection, while IgG alone could indicate recovery or chronic exposure. Negative results don’t rule out infection if symptoms are recent or testing was delayed.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Mycoplasma pneumoniae is a leading cause of atypical pneumonia, often missed on chest X-rays. Antibody testing helps confirm diagnosis when symptoms persist despite antibiotics for bacterial infections. Misdiagnosis can delay appropriate treatment, so results guide further evaluation (e.g., cultures, imaging).

Short name

Mycoplasma pneumoniae antibodies

Frequently asked questions

When might I get false-positive or false-negative results?
False positives can occur with other respiratory infections (e.g., COVID-19, influenza) or cross-reactions. False negatives may happen if testing is done too early (before antibody development) or if the infection was mild. Discuss results with your doctor to interpret them in context.
How long do results take?
Results are typically available within 2–3 business days, depending on lab processing times. Follow-up with your healthcare provider to discuss findings and next steps.
Can I take antibiotics before this test?
Yes, but inform your doctor beforehand. Antibiotics may affect test accuracy by altering antibody levels, so timing is important for accurate diagnosis.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy