Arterial Blood Carbon Dioxide Partial Pressure (PaCO₂)
This test measures the amount of carbon dioxide in your blood taken from an artery, often done during monitoring for breathing or heart conditions.
["Helps assess how well your lungs are removing CO₂ and your body’s acid-base balance."]
Key facts at a glance
- LOINC
- 76172-6
- Short code
- Resp rate CO2 meas
- Synonyms
- Resp rate CO2 meas
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 22
- Ref high
- 28
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- carbon-dioxide-measurement
- CPT
- 82374
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why It’s Done
Your healthcare provider may order this test if you have symptoms like shortness of breath, rapid breathing, chest pain, or if you’re at risk for conditions like respiratory failure, heart disease, or kidney problems. It’s also used during surgeries, intensive care, or before procedures that require deep sedation.
What to Expect
A small needle is inserted into an artery (often in your wrist or arm) to draw a blood sample. You may feel a brief pinch, but the procedure is quick. The test is usually done in a hospital or clinic setting.
Interpretation Basics
Results help determine if your lungs are working properly or if your body is retaining too much CO₂, which can affect your blood pH. Abnormal levels may indicate issues like hyperventilation, lung disease, or metabolic conditions.
Common Conditions Linked to Results
High PaCO₂ levels (hypercapnia) can cause respiratory acidosis, leading to fatigue, confusion, or even coma. Low levels (hypocapnia) may suggest overbreathing or lung overinflation. Your provider will discuss findings in relation to your symptoms and medical history.
Reference range
Adult: 22-28 mmol/LN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
PaCO₂
Frequently asked questions
What does a normal PaCO₂ level mean for me?
How often will I need this test?
Can I prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy