Skip to content

Reticulin Immunoglobulin G (IgG) Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody, in your serum. Reticulin is a protein found in connective tissue, and this test may be used to evaluate conditions affecting connective tissue or immune function.

Quick summary

["This test helps assess immune responses or connective tissue disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31584-6
Short code
Reticulin IgG Ser-aCnc
Synonyms
Reticulin IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms or conditions linked to immune system activity or connective tissue diseases, such as autoimmune disorders, certain cancers, or chronic inflammatory conditions. It may also be part of a broader evaluation for unexplained symptoms like fatigue, joint pain, or unexplained weight changes.

What Does the Test Involve?

A blood sample is drawn from a vein in your arm. The blood is processed to separate serum, which is then analyzed for IgG levels using an immunoassay method. This process is typically quick and painless, with minimal discomfort.

What Should You Know Before the Test?

No special preparation is usually needed, but inform your healthcare provider about any medications you’re taking, especially those affecting immune function or blood clotting. Avoid alcohol before the test if instructed.

What Are Common Results?

Results are compared to a reference range specific to IgG levels in serum. Elevated or low levels may indicate underlying health concerns that require further medical evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated IgG levels may suggest an overactive immune response, such as in autoimmune diseases (e.g., lupus, rheumatoid arthritis) or certain infections. Low levels could indicate immune deficiencies or other systemic conditions. Reticulin itself is not directly measured here, but elevated IgG may indirectly reflect connective tissue involvement or immune activation. Always consult your provider for interpretation.

Short name

Reticulin IgG

Frequently asked questions

What does an abnormal IgG level mean?
An abnormal IgG level may signal an immune system issue, such as an autoimmune disease, infection, or other conditions affecting antibody production. Your provider will discuss these findings with you and may recommend additional tests or treatments.
Can diet or supplements affect this test?
Some supplements or medications that boost immune function (e.g., certain vitamins, herbal supplements) could influence IgG levels. Always inform your healthcare provider about all medications or supplements you take before testing.
Is this test painful?
The blood draw itself may cause mild discomfort, but the test itself is painless. Most people experience only a small bruise or slight soreness at the injection site, which typically fades quickly.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy