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Retinol-binding protein mass concentration (serum/plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of retinol-binding protein in your blood, which helps transport vitamin A. It may be used to assess liver function, vitamin A status, or kidney function.

Quick summary

["RBP levels can indicate how well your body is using vitamin A or if there’s a problem with your liver or kidneys."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
33782-4
Short code
Retinol Bind Prot Ur-mCnc
Synonyms
Retinol Bind Prot Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
38
Ref high
98
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test if you have symptoms like fatigue, vision changes, or unexplained weight loss. It could also be part of a broader evaluation for liver disease, kidney problems, or vitamin A deficiency. Some conditions, like nephrotic syndrome or certain liver disorders, can affect RBP levels.

What Does a Low or High Level Mean?

Low levels of RBP might suggest liver disease, kidney problems, or vitamin A deficiency. High levels could be linked to conditions like nephrotic syndrome, where the kidneys lose too much protein into urine.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed using a specialized technique to measure RBP concentration.

What Are Common Causes of Abnormal Results?

Abnormal RBP levels can result from liver disease (such as cirrhosis), kidney disease, vitamin A deficiency, or certain genetic conditions. Rarely, it may also be affected by medications or pregnancy.

Reference range

NCBI: Vitamin A 38-98 µg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: When This Test Matters

Short name

Retinol-binding protein (RBP) level

Frequently asked questions

When would you need to discuss abnormal results with your doctor?
If your RBP level is significantly low, it may signal a need for further testing of your liver or kidneys. If levels are high, your doctor might investigate kidney function or other underlying conditions.
How often should I expect this test?
This test is often done as part of a routine checkup or when symptoms suggest liver, kidney, or vitamin A issues. Your doctor will determine how often it’s needed based on your health status.
What should I do if I have concerns about my results?
If you have questions about your results, ask your healthcare provider for clarification. They can help explain what the numbers mean in the context of your overall health and recommend next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy