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Liver Biopsy, Radiographic/Fluoroscopic-Guided, with Intravenous Contrast

Published: August 9, 2026Updated: August 16, 2026

An X-ray-guided liver biopsy uses intravenous contrast and imaging guidance to obtain liver tissue for diagnostic evaluation.

Quick summary

["This procedure collects a small liver sample for examination under X-ray guidance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44225-1
Short code
RF Guided Liver Bx--W contr IV
Synonyms
RF Guided Liver Bx--W contr IV
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rf
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a minimally invasive liver biopsy performed with radiographic or fluoroscopic guidance. Intravenous contrast may be given to help the team identify the area of the liver to be sampled.

Why might I need this test?

A liver biopsy may be recommended to evaluate a suspicious liver mass, unexplained liver abnormalities, or conditions involving inflammation, infection, or scarring. The tissue sample can help identify the cause of these findings.

How is the test performed?

After numbing the skin, the clinician positions imaging equipment and may administer intravenous contrast. A needle is then guided through the skin into the liver to collect a small tissue sample, which is sent to a laboratory for examination.

How do I prepare for the test?

Follow the procedure team's instructions about fasting, medications, and blood tests. Tell them about bleeding problems, kidney disease, contrast allergies, or possible pregnancy, and do not stop prescribed medicines unless instructed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

RF-guided liver biopsy with IV contrast

Frequently asked questions

Is this the same as a surgery procedure?
No. It is usually a needle biopsy performed through the skin with imaging guidance rather than an operation requiring an incision.
Why is intravenous contrast used?
Contrast can help show blood vessels and the intended biopsy location on imaging. It is not always needed for every liver biopsy.
What happens to the tissue sample?
The sample is examined by a pathologist, who evaluates the liver tissue for disease and may perform additional specialized tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy