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Routine Fluoroscopic Upper GI Series with Water-Soluble Contrast, Oral

Published: August 9, 2026Updated: August 16, 2026

An X-ray study of the upper digestive tract performed after swallowing water-soluble contrast, which outlines the esophagus, stomach, and duodenum.

Quick summary

["This imaging test helps identify structural or functional problems in the esophagus, stomach, and upper small intestine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42012-5
Short code
RF UGI Views W H2O soluble contr PO
Synonyms
RF UGI Views W H2O soluble contr PO
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rf
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a fluoroscopic X-ray examination of the upper gastrointestinal tract. You swallow a water-soluble contrast liquid, and a radiologist watches the contrast move through your esophagus, stomach, and duodenum while taking images.

Why might I need this test?

It may be ordered to investigate difficulty swallowing, persistent vomiting, upper abdominal pain, reflux symptoms, or suspected ulcers, narrowing, tumors, or problems with stomach emptying.

How is the test performed?

You drink a measured amount of contrast and then change positions as directed while X-ray images are recorded. The images show the shape and movement of the upper digestive tract. The examination usually takes less than an hour.

How do I prepare for the test?

Follow the preparation instructions provided by the imaging center, which may include fasting or limiting solid food and drinks beforehand. Tell the care team about contrast allergies, kidney disease, pregnancy or possible pregnancy, swallowing difficulties, and any prior reactions to contrast.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal findings may indicate reflux, ulcers, narrowing or strictures, hiatal hernia, tumors, or delayed movement of contrast through the stomach. Results are interpreted together with your symptoms, examination, and any other tests. Your radiologist will explain the findings and recommend follow-up if needed.

Short name

Upper GI series with oral water-soluble contrast

Frequently asked questions

Is this the same as a barium swallow?
It is similar in principle, but this study uses water-soluble contrast rather than a thicker barium mixture. Water-soluble contrast is often used when the study needs to be performed safely without using barium.
Will I feel anything after drinking the contrast?
The contrast may taste unpleasant and feel chalky. Some people notice mild nausea, abdominal fullness, or a need to burp, but serious reactions are uncommon.
Can I return to my normal activities afterward?
Most people can resume normal activities right away. Follow any specific instructions from the imaging center, especially if you were given sedating medication or have another medical condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy