Rh D Alloantibody Detection by Latex Agglutination (Blood Sample)
This test checks for the presence of antibodies against the RhD antigen in your blood, which can occur after blood transfusions, pregnancy, or certain blood disorders. It helps prevent complications like hemolytic disease of the fetus and newborn.
["Identifies RhD antibodies that may cause serious blood compatibility issues."]
Key facts at a glance
- LOINC
- 35465-4
- Short code
- RHD allele Geno Bld/T
- Synonyms
- RHD allele Geno Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters for Blood Safety
Your healthcare provider may order this test if you’ve had a blood transfusion, are pregnant, or have a history of red blood cell problems. It ensures your blood is compatible for future transfusions or pregnancy care.
How the Test Works
A small sample of your blood is mixed with RhD-coated latex particles. If antibodies are present, they bind to the particles, causing them to clump. This clumping is detected visually or through a machine.
What to Expect Before the Test
No special preparation is needed. You may have a small needle inserted into your arm to draw blood, similar to other routine blood tests. The process usually takes a few minutes.
Possible Results and Next Steps
A positive result means antibodies are detected. Your doctor will discuss next steps, which may include further testing or adjustments to your treatment plan, such as avoiding certain blood products.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
RhD antibodies can lead to severe reactions if exposed to RhD-positive blood during transfusions or during pregnancy, potentially causing anemia or other complications in the fetus. This test is critical for managing patients with blood disorders, those who’ve had transfusions, or those who are pregnant to ensure safe blood compatibility.
Short name
RhD Antibody Screen (Serum/Plasma)
Frequently asked questions
What does a positive result mean?
Can I avoid this test if I’ve never had a transfusion or pregnancy?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy