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Rhesus D Antibody Screening (Qualitative) with Specimen Probe

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of antibodies against the Rhesus D antigen, which can affect blood compatibility during pregnancy or transfusions.

Quick summary

["This screening helps prevent complications from Rh incompatibility, a condition where a mother’s immune system reacts to her baby’s blood type."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95360-4
Short code
RHDV2 RNA Ct Spec Qn NAA+probe
Synonyms
RHDV2 RNA Ct Spec Qn NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Pregnancy

Rh incompatibility can occur if a mother is Rh-negative (lacking the D antigen) and her baby is Rh-positive (has the D antigen). During pregnancy, the mother’s immune system may produce antibodies against the baby’s blood cells, potentially causing issues like anemia or severe complications if detected early.

How the Test Works

A small sample of your blood is tested using an immunoassay method to detect RhD antibodies. If antibodies are found, it confirms the need for further testing or monitoring, such as Rh immune globulin (RhIG) administration during pregnancy.

When You Might Need This Test

This test is typically ordered during pregnancy, especially if you are Rh-negative, or if you have a history of miscarriage, stillbirth, or other complications. It may also be done before blood transfusions to ensure compatibility.

What to Expect During the Test

You will have a simple blood draw, usually from a vein in your arm. The process takes a few minutes, and you may feel a slight pinch. No special preparation is needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

RHD Antibody Screen (Qual)

Frequently asked questions

When should I expect results from this test?
Results are usually available within 1–3 business days, depending on lab processing times. Your healthcare provider will contact you with the results and next steps.
What does a positive result mean?
A positive result indicates the presence of RhD antibodies in your blood. This means you may need additional monitoring, such as Rh immune globulin during pregnancy, to protect your baby’s blood cells.
Can I still have a healthy pregnancy if I have Rh antibodies?
Yes, with proper management—such as Rh immune globulin injections during pregnancy and regular ultrasounds—to minimize risks. Your healthcare provider will tailor a plan based on your specific situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy