Rho(D) Antibody Titration (Serum)
This test measures the amount of antibodies against the Rh(D) antigen in your blood, which helps determine your risk of developing Rh incompatibility during pregnancy or blood transfusions.
["Helps prevent complications from Rh factor mismatches in pregnancy or bloodwork."]
Key facts at a glance
- LOINC
- 23575-4
- Short code
- RHDV Ab Titr Ser
- Synonyms
- RHDV Ab Titr Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters for Pregnancy
If you’re pregnant or planning pregnancy, this test is crucial for identifying whether you have developed antibodies against the Rh(D) antigen. Rh incompatibility can occur if your blood type is negative (Rh-negative) and your baby’s blood type is positive (Rh-positive). Without this test, your doctor may not detect early signs of complications like anemia or other issues in your baby.
How the Test Works
Your blood sample is tested using an immunoassay method to detect and quantify Rh(D) antibodies. The result helps your healthcare provider assess your risk for potential complications and guide appropriate care, such as Rh immune globulin (RhIG) treatment if needed.
When You Might Need This Test
You may need this test if you’ve had a previous pregnancy with an Rh-positive baby, miscarriage, stillbirth, or blood transfusion. It’s also commonly ordered during the first trimester of pregnancy for Rh-negative women to monitor for Rh antibodies.
What to Expect Before the Test
No special preparation is needed for this test. A blood sample is drawn from a vein in your arm, similar to other routine blood tests. You may feel a slight pinch, but it usually takes only a few minutes to complete.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Rho(D) Antibody Level
Frequently asked questions
If your Rh(D) antibody level is low or undetectable, you’re unlikely to have complications. However, if the level rises significantly, it may indicate the development of Rh antibodies, which can pose risks to future pregnancies or blood transfusions. Your doctor will discuss next steps based on the results.
What does a high or low Rh(D) antibody level mean?
Can I avoid this test if I’ve had Rh immune globulin (RhIG) treatment?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy