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Rhodamine-based Fluorescent Immunoassay for Antinuclear Antibodies (ANA) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies in your blood that may target proteins in your nucleus, helping identify conditions like lupus or other autoimmune diseases.

Quick summary

["Helps detect autoimmune disorders by checking for unusual antibodies in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92804-4
Short code
Rhodatorula DNA Bld Pos Ql NAA+probe
Synonyms
Rhodatorula DNA Bld Pos Ql NAA+probe
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Autoimmune diseases occur when your immune system mistakenly attacks healthy cells in your body. This test detects specific antibodies (antinuclear antibodies, or ANA) that can signal such conditions. While not all positive results mean you have an autoimmune disease, they may prompt further testing.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from your arm. The test looks for antibodies in your serum using a fluorescent probe to identify their presence.

How the Results Are Used

Results help doctors assess whether you have an autoimmune condition or another underlying issue. A positive result may lead to additional tests, like checking for specific antibodies or symptoms of disease.

Common Conditions Linked to Positive Results

Positive ANA results are common in autoimmune diseases such as lupus, rheumatoid arthritis, or Sjogren’s syndrome. However, some healthy people also test positive, so results are interpreted alongside other factors like symptoms and further testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: ANA Testing Explained

Short name

ANA Fluorescent Probe Test

Frequently asked questions

What does a positive result mean?
A positive ANA test means your blood contains antibodies that target nuclear components in cells. This can indicate an autoimmune response, but it doesn’t confirm a specific diagnosis. Doctors use the result alongside symptoms, other tests, and patient history to guide further evaluation.
How often should I get this test?
Your doctor will determine the frequency based on your symptoms, medical history, and other test results. Some people may need periodic monitoring, while others may only need it once to rule out certain conditions.
Can I take anything to lower my ANA levels?
There’s no known way to reduce ANA levels naturally. If your test is positive, focus on managing symptoms and working with your healthcare team to address any underlying conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy