Skip to content

Ribosomal RNA (16S) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of ribosomal RNA, a key component of cells, in your blood. It may be used to assess certain infections, immune responses, or metabolic conditions.

Quick summary

["This test helps doctors evaluate cellular activity or infections in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63320-6
Short code
Ribosomal Ab Fld Ql IF
Synonyms
Ribosomal Ab Fld Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test if they suspect an infection (such as bacterial or viral), an immune disorder, or a condition affecting cell function. It can also be part of research studies or specialized diagnostics.

What Does the Test Involve?

A blood sample is drawn from a vein, typically in your arm. The sample is then processed to detect ribosomal RNA, often using advanced laboratory techniques like next-generation sequencing or specialized immunoassays.

Sample Collection and Preparation

The test uses either serum (blood without clotting factors) or plasma (blood with clotting factors removed). The sample is sent to a lab where it is analyzed for specific ribosomal RNA fragments.

What Are Possible Results?

Results may show elevated or altered levels of ribosomal RNA, which can indicate abnormal cell activity, infection, or other underlying health issues. Interpretation depends on clinical context and comparison to known reference ranges for this specific test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is primarily used in research or specialized diagnostics to study cellular processes, infections, or immune responses. Elevated ribosomal RNA levels may suggest active infection, inflammation, or certain metabolic disorders. It is not a routine diagnostic tool for most conditions and requires clinical correlation.

Short name

Ribosomal RNA (16S) Test

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result may indicate an infection, immune response, or other cellular activity that warrants further investigation by your healthcare provider. They will discuss the results in detail based on your medical history and symptoms.
How often will I need this test?
The frequency depends on your healthcare provider’s recommendations. This test may be part of a research study or a one-time diagnostic evaluation rather than a routine check.
Is there any preparation needed before the test?
No special preparation is typically required, but you may be asked to fast or avoid certain medications depending on the specific clinical context. Always follow your provider’s instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy