###1: Ribosomal P Antibody, Serum
This blood test checks for ribosome-related P antibodies, which are autoantibodies made by the immune system. A positive result may occur in autoimmune conditions, most often primary Sjögren syndrome, but it must be interpreted with symptoms and other test results.
["###4: A positive result can support an autoimmune diagnosis, but it does not identify a specific disease by itself."]
Key facts at a glance
- LOINC
- 13636-6
- Short code
- Ribosomal P Ab Ser-aCnc
- Synonyms
- Ribosomal P Ab Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
###5: What the test measures
###6: The test measures ribosome P antibodies in serum. These antibodies target proteins associated with cellular ribosomes, which are structures that make proteins.
###7: Why it may be ordered
###8: A clinician may order this test when symptoms suggest an autoimmune connective-tissue disorder, particularly primary Sjögren syndrome. It may also be considered when results for other antibodies or disease markers do not fully explain the patient's symptoms.
###9: Interpreting the result
###10: A positive result means ribosome P antibodies are present. Antibodies can also be found in some healthy people or in other autoimmune diseases, so the result should be interpreted with the clinical findings and other laboratory tests rather than used alone.
###11: Related conditions
###12: Ribosomal P antibodies are most strongly associated with primary Sjögren syndrome. They may occasionally be present in systemic lupus erythematosus, autoimmune liver disease, or other autoimmune conditions.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
###13: Clinical significance: Detection of ribosome P antibodies can provide evidence of autoimmunity and may support a diagnosis of primary Sjögren syndrome in an appropriate clinical context. However, the test is not definitive on its own, and a positive result does not establish which organ systems are affected or how severe the disease will be.
Short name
Ribosomal P antibody
Frequently asked questions
###14: Does a positive result mean I have Sjögren syndrome?
###16: Can I have this test without symptoms?
###18: What other tests might be ordered with it?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy