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Rickettsiabldcult

Published: August 9, 2026Updated: August 17, 2026

This test detects Rickettsia bacteria in your blood to diagnose infections transmitted by ticks, fleas, or lice.

Quick summary

{"Detects Rickettsia bacteria in whole blood sample","Used to diagnose infections like Rocky Mountain spotted fever and typhus","Results help doctors choose the right antibiotic treatment","Early testing is important as symptoms can become severe","Sample is collected by drawing blood from a vein"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
5878-4
Short code
RICKCUL
Synonyms
Rickettsia Bld Cult
Category
cardiac
Sample
whole-blood
Container
Sterile blood culture bottle (aerobic) or sterile evacuated tube with EDTA
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
organism-specific-culture
CPT
87015
SNOMED
122442004
Specimen volume
10-20 mL of whole blood for optimal culture sensitivity
Stability
Room temperature: 2-8 hours; Refrigerated: 24-48 hours. Transport to laboratory promptly.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
72–168 hours
Order
routine

What is this test?

The Rickettsia blood culture test is a laboratory test that looks for Rickettsia bacteria in your blood. Rickettsia are a type of bacteria that can cause serious infections when transmitted to humans through bites from infected arthropods such as ticks, fleas, lice, or mites. This test uses a special culture method to grow and identify the specific Rickettsia organism present in your blood sample.

Why might I need this test?

Your doctor may order this test if you have symptoms of a Rickettsial infection, especially if you have been exposed to areas where these infections are common or have recently been bitten by ticks, fleas, or lice. Common symptoms include high fever, severe headache, rash, muscle pain, and sometimes a distinctive spotted rash. This test is particularly important because Rickettsial infections can become life-threatening if not treated promptly with the right antibiotics.

How is the sample collected?

A healthcare professional will draw a small amount of blood from a vein in your arm using a needle. The blood sample is then placed in a special container and sent to a laboratory where it is cultured (grown) under specific conditions to detect any Rickettsia bacteria present. The process may take several days to a couple of weeks because Rickettsia bacteria grow slowly in culture.

What do the results mean?

A positive result means that Rickettsia bacteria have been identified in your blood, confirming a Rickettsial infection. The test can also identify the specific type of Rickettsia, which helps your doctor determine the exact disease and choose the most appropriate treatment. A negative result does not completely rule out infection, as the bacteria may not be present in sufficient numbers in the blood at the time of testing, or the infection may be in its early stages. Your doctor will interpret the results together with your symptoms and other test findings.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: whole-blood

No special preparation required. Inform laboratory of recent travel history, exposure to tick bites, or areas endemic for rickettsial diseases. Standard venipuncture precautions apply.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is this test painful?
You may feel a brief sting or pinch when the needle is inserted to draw your blood. The procedure typically takes only a few minutes. Some people may experience minor bruising at the puncture site afterward.
How long does it take to get results?
Results may take longer than typical blood tests because Rickettsia bacteria grow slowly in culture. It typically takes 7-14 days to get results, though this may vary depending on the laboratory.
Do I need to prepare for this test?
No special preparation is usually required. You should inform your doctor about any medications you are taking, as some antibiotics may affect test results. It is also important to tell your doctor if you have any bleeding disorders or are taking blood thinners.
What happens if the test is positive?
If the test confirms a Rickettsial infection, your doctor will prescribe specific antibiotics, typically doxycycline, which is the treatment of choice for most Rickettsial diseases. Early treatment is essential for a good outcome, so treatment may begin before final results are available if your doctor strongly suspects the infection.
Can Rickettsial infections be prevented?
Prevention includes using insect repellent, checking for ticks after outdoor activities, wearing protective clothing, and keeping living areas clean to control rodents and fleas. If you live in or travel to areas where Rickettsial diseases are common, take preventive measures and seek medical attention promptly if you develop symptoms after a tick or insect bite.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy